A medley of spices fills the air as I sauté tender chicken, bringing the essence of the Southwest right to my kitchen. This Cheesy Southwest Skillet Chicken has become my go-to one-pan meal for busy evenings when I crave something satisfying without the fuss. It effortlessly blends juicy chicken with vibrant veggies and an irresistible creamy sauce that makes every bite a delight. The best part? It’s not just quick to whip up, but it also allows for endless variations; you can make it extra spicy or even swap in your favorite proteins. Whether you’re feeding a crowd or simply treating yourself, this comforting dish will soon become a favorite on your table. Are you ready to dive into this cheesy, flavorful creation? Let’s get cooking!

Why is this dish a must-try?

One-Pan Wonder: This Cheesy Southwest Skillet Chicken simplifies weeknight cooking, combining all your ingredients in a single skillet for easy cleanup.
Flavor Explosion: A blend of spices creates a fiesta of flavors that dances delightfully on your palate, making every bite exciting!
Customizable Options: Switch up your spice level or protein with ease—whether it’s shrimp, tofu, or extra veggies, the possibilities are endless.
Quick Preparation: Whip it up in no time, perfect for busy evenings when you want comfort without the hassle. If you love other easy meals, check out this Bruschetta Chicken Pasta for another crowd-pleaser!
Crowd-Pleasing Comfort: Everyone from kids to adults loves this recipe, making it a surefire hit for family dinners or gatherings. With its creamy richness, it’s bound to leave everyone wanting seconds!

Cheesy Southwest Skillet Chicken Ingredients

• Let’s gather the essentials for this creamy one-pan meal!

For the Chicken

Chicken: 1.5 lbs boneless, skinless chicken breasts or thighs, cut into 1-inch pieces – thighs offer more moisture for a tender bite.
Olive Oil: 1 tablespoon – perfect for searing chicken and imparting flavor; any neutral oil will work as a substitute.
Salt and Black Pepper: To taste – essential for enhancing all the flavors in your dish.

For the Seasoning

Chili Powder: 1 teaspoon – provides the signature Southwest flavor; consider smoked chili powder for added depth.
Ground Cumin: 1/2 teaspoon – enhances warmth and earthiness; no direct substitute, but coriander can offer a different twist.
Garlic Powder: 1/2 teaspoon – great for seasoning; fresh garlic is an excellent substitute for a bolder taste.
Onion Powder: 1/4 teaspoon – complements the seasoning blend; use fresh chopped onions for a different texture if desired.

For the Filling

Corn: 1 cup frozen or canned corn, drained – adds sweetness and texture; feel free to swap with peas for variation.
Bell Peppers: 1/2 red and 1/2 green, diced – ensures color and crunch; use any color or try zucchini for a twist.

For the Sauce

All-purpose Flour: 2 tablespoons – forms the roux for creaminess; opt for gluten-free flour or cornstarch with water as a substitute.
Chicken Broth: 1 cup – creates the sauce base; vegetable broth is a good choice for a vegetarian version.
Cream Cheese: 1/4 cup, softened – adds rich creaminess; Greek yogurt can lighten it up for a healthier option.
Shredded Cheese: 2 cups mozzarella or Mexican blend, for topping – switch to Monterey Jack or Pepper Jack for a spicier kick.

Get ready to enjoy the delicious flavor of Cheesy Southwest Skillet Chicken!

Step‑by‑Step Instructions for Cheesy Southwest Skillet Chicken

Step 1: Prepare the Chicken
Start by patting the 1.5 lbs of boneless, skinless chicken breasts or thighs dry with paper towels. In a mixing bowl, toss the chicken pieces with 1 tablespoon of olive oil, 1 teaspoon of chili powder, 1/2 teaspoon of ground cumin, 1/2 teaspoon of garlic powder, and salt and black pepper to taste. Ensure each piece is well-coated with the spices, enhancing the flavors in your Cheesy Southwest Skillet Chicken.

Step 2: Sear the Chicken
Heat an oven-safe skillet over medium-high heat for about 2 minutes, until hot. Add the seasoned chicken in a single layer, searing for 2-3 minutes on each side until golden brown. You want a nice crust to form. Once seared, remove the chicken from the skillet and set aside on a plate while you prepare the veggies, keeping the skillet warm to retain the heat.

Step 3: Sauté the Vegetables
In the same skillet, add diced bell peppers (1/2 red and 1/2 green) and 1 cup of frozen or canned corn, drained. Sauté the vegetables for 3-5 minutes over medium heat until tender and slightly caramelized. This step infuses the skillet with delicious flavors while preparing a vibrant mix that complements your Cheesy Southwest Skillet Chicken.

Step 4: Create the Roux
Sprinkle 2 tablespoons of all-purpose flour over the sautéed veggies and stir for about 1 minute, allowing the flour to cook. Gradually whisk in 1 cup of chicken broth, stirring constantly until the mixture thickens and bubbles form. This roux will create a creamy base for your sauce, preparing it to embrace the chicken as you continue with the recipe.

Step 5: Add Creaminess
Lower the heat and mix in 1/4 cup of softened cream cheese, stirring until it fully melts and blends into the sauce. Return the seared chicken to the skillet, ensuring the pieces are submerged in the creamy sauce. This step transforms your Cheesy Southwest Skillet Chicken, making it irresistibly rich and flavorful, ready for the next phase.

Step 6: Top with Cheese and Bake
Preheat your oven to 375°F (190°C). Once your chicken is in the sauce, sprinkle 2 cups of shredded cheese over the top. Transfer the skillet to the oven and bake for 15-20 minutes, or until the chicken is cooked through (an internal temperature of 165°F/74°C) and the cheese is melted and bubbly. This will create a delightful cheese crust that adds texture to your dish.

Step 7: Serve and Enjoy
Let the Cheesy Southwest Skillet Chicken rest for a few minutes after removing it from the oven. This helps the flavors settle and makes it easier to serve. Prepare your favorite sides, maybe some fluffy rice or warm tortillas, and enjoy this comforting meal with family or friends.

Make Ahead Options

These Cheesy Southwest Skillet Chicken options are perfect for busy home cooks looking to save time! You can chop the bell peppers and gather all your seasonings up to 24 hours in advance, refrigerating them in an airtight container to maintain freshness. Additionally, you may marinate the chicken pieces in the olive oil and spices the night before, enhancing the flavor while streamlining dinner prep. When ready to cook, simply follow the remaining steps by sautéing the veggies and creating the sauce—everything will still taste just as delicious! For a full meal prep, this dish can also be assembled completely up to 3 days ahead and stored in the fridge; just bake before serving for that irresistible cheesy finish!

What to Serve with Cheesy Southwest Skillet Chicken

There’s nothing like creating a beautiful spread around a dish that bursts with flavors and textures!

Fluffy Rice: Acts as a comforting base, perfect for soaking up the creamy sauce and bringing a soothing touch to your meal.
Warm Tortillas: Ideal for scooping or wrapping, these soft bites add a delightful element of fun and versatility to every serving.
Crisp Green Salad: A colorful medley of fresh greens and veggies offers a refreshing contrast to the richness of the skillet dish, brightening each bite.
Seasoned Black Beans: Their hearty texture and earthy flavor perfectly complement the Southwestern spices, making for a balanced plate that satisfies all cravings.
Guacamole: Creamy and rich, a side of guacamole enhances the flavor profile and elevates the overall experience with its refreshing touch.
Tropical Fruit Salsa: The sweetness of mango or pineapple salsa provides a luscious contrast, cutting through the dish’s creaminess for a delightful pop.
Margaritas or Sparkling Water: A bright drink, whether it be a classic margarita or a refreshing sparkling water, adds a vibrant touch that rounds out the meal beautifully.
Chocolate Churros: End the dinner on a decadent note; these crispy, cinnamon-dusted treats bring warmth and sweetness, making them an irresistible dessert choice.

How to Store and Freeze Cheesy Southwest Skillet Chicken

Fridge: Store leftovers in an airtight container for up to 3 days. Reheat in the microwave or on the stovetop until warmed through.

Freezer: For longer storage, freeze Cheesy Southwest Skillet Chicken in individual portions for up to 3 months. Thaw in the fridge overnight before reheating.

Reheating: Gently reheat in the oven at 350°F (175°C) until heated through, or microwave in increments, stirring occasionally. Add a splash of broth if the sauce seems thick.

Cheesy Southwest Skillet Chicken Variations

Feel free to put your own spin on this delightful dish—there’s so much room for creativity that your taste buds will thank you!

Spicy Kick: Add minced jalapeños or a pinch of cayenne pepper to the spice mix for a fiery touch. This boosts the flavor and brings a refreshing heat to the creamy sauce.
Seafood Twist: Substitute chicken with shrimp or firm tofu for a seafood or vegetarian option. Both alternatives will absorb the delicious flavors of the sauce while providing a satisfying texture.
Add More Veggies: Toss in some fresh spinach or kale before melting the cheese for a nutrient-rich variation. Not only will it enhance the nutritional profile, but it also adds a vibrant color to your dish.
Creamy Greek Delight: Swap cream cheese with Greek yogurt for a tangy, lighter sauce. This transformation will maintain creaminess while offering a healthier alternative.
Zesty Citrus Flavor: Incorporate the zest of a lime or lemon into the sauce for a burst of brightness. The citrus notes will elevate the overall flavor and add a lovely fresh twist.
Cheese Variety: Try using sharp cheddar or Pepper Jack instead of mozzarella, bringing a bolder, cheesier punch to your dish. The gooeyness coupled with a spicier flavor will surely be a hit!
Gluten-Free Option: Use a gluten-free flour blend or cornstarch mixed with water to create a smooth roux if you’re making a gluten-free version. This way, everyone can enjoy the creamy goodness!
Meat Combo: Mix in cooked chorizo or ground turkey alongside chicken for a hearty, protein-packed meal that brings even more flavor to the party. Each bite will be savory and hearty, perfect for those who love variety.

Whichever variation you choose, your cozy Southwest dinner will surely become a family favorite. If you’re looking for more delicious ideas, this Peruvian Chicken Meatballs will also spice up your dinner menu!

Expert Tips for Cheesy Southwest Skillet Chicken

Hot Skillet First: Ensure your skillet is preheated properly before adding the chicken to achieve that perfect sear and lock in moisture.
Don’t Overcrowd: Avoid placing too many chicken pieces in the skillet at once; this can lower the temperature and lead to steaming, making them dry instead of juicy.
Use a Thermometer: An instant-read thermometer is your best friend—ensure chicken reaches an internal temperature of 165°F (74°C) for safe and perfectly cooked Cheesy Southwest Skillet Chicken.
Adjust Sauce Consistency: If the sauce becomes too thick as it cooks, simply add a splash more chicken broth to achieve your desired texture without losing creaminess.
Tailor the Spice Level: Feel free to customize the heat by adjusting the amount of chili powder or adding minced jalapeños or cayenne pepper to suit your taste preferences.

Cheesy Southwest Skillet Chicken Recipe FAQs

What type of chicken should I use for this recipe?
You can use 1.5 lbs of boneless, skinless chicken breasts or thighs. I recommend thighs for their juiciness, but breast meat works just fine too!

How should I store leftovers of Cheesy Southwest Skillet Chicken?
Store any leftovers in an airtight container in the fridge for up to 3 days. Reheating is easy—just pop it in the microwave or warm it on the stovetop until heated through, and enjoy!

Can I freeze Cheesy Southwest Skillet Chicken?
Absolutely! To freeze, divide the dish into individual portions and store them in freezer-safe containers for up to 3 months. When you’re ready to enjoy, thaw overnight in the fridge, then reheat in the oven at 350°F (175°C) for best results.

How can I adjust the spice level in this recipe?
To personalize the heat level, feel free to add minced jalapeños or a pinch of cayenne pepper to the spice mix. For an extra kick, consider adding more chili powder according to your preference.

What should I do if my sauce turns out too thick?
If your sauce has become too thick, don’t worry! Just add a splash of chicken broth while stirring on low heat until you reach your desired consistency. This simple adjustment will help you keep that creamy texture while enhancing the flavors.

Is this recipe suitable for dietary restrictions?
Yes! You can easily make this Cheesy Southwest Skillet Chicken gluten-free by substituting all-purpose flour for a gluten-free blend or cornstarch mixed with water. Additionally, if you’re looking for a vegetarian version, just swap the chicken for firm tofu or shrimp!